Code
Hierarchy
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C00-D49 Neoplasms (C00-D49)
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D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
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D48 Neoplasm of uncertain behavior of other and unspecified sites
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D48.0 Neoplasm of uncertain behavior of bone and articular cartilage
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D48.1 Neoplasm of uncertain behavior of connective and other soft tissue
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D48.2 Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
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D48.3 Neoplasm of uncertain behavior of retroperitoneum
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D48.4 Neoplasm of uncertain behavior of peritoneum
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D48.5 Neoplasm of uncertain behavior of skin
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D48.6 Neoplasm of uncertain behavior of breast
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D48.7 Neoplasm of uncertain behavior of other specified sites
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D48.9 Neoplasm of uncertain behavior, unspecified
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Notes
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Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
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Functional activity
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All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
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Morphology [Histology]
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Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
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Primary malignant neoplasms overlapping site boundaries
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A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
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Malignant neoplasm of ectopic tissue
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Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
- C25.9 Malignant neoplasm of pancreas, unspecified